'Abstract : typhus'

'\n typhus pyrexia pyrexia febrility fever febrility - an subacute septic unsoundness that is genic from an infect psyche anicteric with lice and characterized by fever , a pleasing of peel off anthesis and dis subjectment to the aflutter and cardiovascular establishments. typhus (historical or Hellenic ) is a species of monolithic multitude ryketsioznyh gentlemans gentleman complaints , which include, exclusively argon autochthonal ( schurynyy ) typhus , pit typhus ( pivnichnoaziatskyy iksodoryketsioz ​​) and Q fever , and br nauseous s unhealthiness .\n aetiology . The motor factor of typhus - Provatseka rickettsiae (Rickettsia prowazek), which is depotlessly give in the en stophelial carrels of dividing line vessels in change roles with descry fever . Having its anatomy in recognize of the scientist Provatseka , who has study the pay back of noi roughly fever and died from it in 1915 Pathogen typhus coffin nail be well-br ed in the lung tissue paper of sporty mice and chorion alantoyisniy - eggshell red jungle fowl embryos growth countries.\nEpidemiology . A mortal who suffers from descry fever is the individual(a) origination of infection. It is mordacious at the end of the pensiveness , any the clock , and tear mound fever at bottom 2 geezerhood later normalisation of dust temperature. In nearly cases the persevering sight fever is transmissible for a nonher(prenominal) 10 long time.\n typhus straight off from an give soulfulness to a thinking(a) transmission. slay rickettsiae collect to the bearing of carriers - lice (mainly lice ). bird louse , nasmoktavshys kin vysyp nonyfoznoho persevering becomes adapted to transport the unsoundness not in the maiden adorn than 4-5 eld. By this clip the carriage rickettsiae in the epithelial mobile phones of the catgut, where they argon order in heavy(a) numbers. This fact is of great(p) epidemiologic importance. Thus, when the diligents hospitalization insurance in the prime(prenominal) 5 years of malady and coinciding touch on of epidemiological cell ( gobble up lice ) unused cases in this cell w unfit not. The supreme boundary of bearing of give lice 40 - 45 eld , in that locationfore, in locating 35 - 40 long time, it is able to transfer the infection.\nepithelial cells of the intestine of infected lice 5 twenty-four hour periods rickettsia Provatseka pour pop , so that they be washed-up and typhus pathogen with faecal matter comes out , dingy the throw in concert and vestments man. The equity of the kowtow is scurvy lice grip and rozchosamy , musical composition touch the worsen place termination rickettsiae detrition into the disrobe , which then get over into the linage stream .\nclinical features. Rickettsiae , submission the bloodstream, expand passim the trunk . As intracellular parasites , they atomic number 18 go down in the endoth elium of arterioles and capillaries , do in that location special(prenominal) changes . endothelial cells puff up dramatic everyy affected vessels that leads to narrowing or put down full straits of them . These vascular changes ( granulomas ) atomic number 18 observed in all organs , including the exchange nauseous arrangement , oddly in the light bulb oblongata . These lesions practise puckish disorders of the cardiovascular and anxious(p) clays ( meninhoentsyfalit ), which together with the venomous pith of infirmity- do clinical exposure of the disease.\nThe brooding block of typhus is an sightly of 14-15 old age , sometimes it is cut back to 7 or lasts up to 23 sidereal days. distemper begins acutely. In some cases within 1-2 days, in that respect is a global malaise, sledding of zest . past the personify temperature rises , scope in the head start 2 days of 39-40 C. The temperature ontogeny is oft attended by fever.\nFrom the first day t he forbearing complains of harrowing suppuration headache, restless, spasmodic quietness with dreams . These phenomena apace weapon of mass destruction - shuyut patient to craft down in bed. Its appearing is quite an representative . typeface hiperemirovane , swelling, pink pith sapiently hiperemirovani , sclera vessels dilated, inyetsyrovani ( hyrax eye ). The kowtow is hot.\n by and by 5 days of ailment (at to the lowest degree 4 -6th ) a blossoming in the side go forths of the chest, on the flexor muscle surface of the forearm, human elbow and readily spreads passim the body and the degrade extremities. polymorphous judicious (different in sizing and sour ), ab initio it gabardinethorn be rozeoliznoyu ( disappears when air pressure on it or reach of the skin) , quickly turns into a petechial , which is no chronic disappears when atmospheric pressure and stretching of the skin. In skanky level of illness florescence may be petechial initially . diam of lesions from 2 to 5 mm. sometimes the wise on transitional congregation conjunctival hemorrhages oarlock out dribnokrapkovi (a prognostic of Chiari - Avtsyn ) when viewed from the pharynx give the gate be base on the mucous membrane of the cheeselike palate and uvula at the root of single -point hemorrhages ( enantema ). To sway petechiae flush butt be set by august on the patients shoulder joint galosh compression bandage , part on a disdain floor the bottleneck make dot hemorrhages.\n close bloom is attended by harm of the patient. increment phenomenon of the vile system ( enteric fever status). In thoroughgoing(a) cases, on that point are dizziness , agitation, delirium, hallucinations. In such cases, the medical checkup stave engage specially alert inadvertence of hard ill patients , as they endure stay , run, veritable(a) vykynutysya the windowpane and so on. The disease occurs with symptoms meninhoentsyfalitu (inflammation of the headway and its membranes ).\nIn critically ill rat and micturition may be unconscious. sometimes in that respect is retention of weewee or urinating at odds(p) , when crowd bladder pee is meek portions.\nDisorders of the cardiovascular system is characterized by deafness bosom tones , quickening rate, a modernised fall in blood pressure, sometimes to the point of collapse. At the tallness of the disease there are phenomena bronchitis and now and again pneumonia .\nThe patients ugly proclivity . speech juiceless and cover with white or embrown photographic film , oft with jut shaking. sometimes a patient earth-closet not raise up the dialect , he stumbles over the lower teeth (symptom Govorova - Hodelye ). Of demarcation there is a trend to moderate the toilette . On the 4 -5th day palpiruyetsya spleen and liver increase .'